The objective of this study is to evaluate the antimalarial property of carica papaya l. Review on nutritional, medicinal and pharmacological. Pdf on jan 10, 2017, okpe oche and others published chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts find, read and cite all the research. Phytochemical screening, antimicrobial and antioxidant. Seeds of papaya cultivated in somalia, which accounted for about 16% of the fresh fruit weight, were divided into sarcotesta and endosperm. Oil extract showed very high levels of oleic and palmitic acids. Since, each part of papaya tree possesses economic value, it is grown on commercial scale. Carica papaya linnaeus, pawpaw, belongs to the family of caricaceae.
Papaya leaves have been used in the treatment of various ailments 2. In this study, we investigated the in vitro cytotoxicity of aqueous and ethanolic extracts of carica papaya leaves on the human oral squamous cell carcinoma scc25 cell line in parallel with noncancerous human keratinocyte hacat cells. Phytochemical screening of the polar extracts of carica. The standard method of analysis used was able to identify really that carica papaya. Antifungal activity in ethanolic extracts of carica papaya. The hypoglycemic activities of carica papaya have been previously described for its fruit and leaves aruoma et al. Resident, 3associate professor, 4professor and head, department of medicine, s. Carica papaya is an evergreen shrub or small tree that.
Lcms spectrum positive mode analysis of extract of leaf of c. Fresh leaves samples of the plant were collected during the month of january, 20 from different parts of bhuj in kachchh district gujarat, india. Chemical composition of various parts of carica papaya linn. The papaya is a large, treelike plant, with a single stem growing from 5 to 10 m 16 to 33 ft tall, with spirally arranged leaves confined to the top of the trunk 5. Phytochemical screening and hypoglycemic activity of. Phytochemical screening, chromatographic studies and. The chemical and pharmacological basis of papaya carica papaya l. Lako, 2007nd egcg persea americana hydromethanolic seed calderonoliver et al. Lmcs spectrum negative mode analysis of extract of leaf of c.
Seeds were extracted from the fruits and the pro ximate, mineral and vitamin analysis carried out on the leaves, fruit s and. Traditional aboriginal preparation alters the chemical. This document provides an overview of baseline biological information relevant to risk assessment of genetically modified forms of the species that may be released into the australian environment. It has been documented in literature for its use by natives of various parts of world and also for its antiinflammatory.
Papaya is not a tree but an herbaceous succulent plants that posses self supporting stems. Biochemical constituents in leaf of carica papaya scipress ltd. Defatted and undefatted seeds of papaya carica papaya were analyzed for proximate composition, some toxicants, sugar composition, mineral content, physicochemical properties of the seed oil and the fatty acid spectrum of the seed oil. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and crude fibre 226% undefatted, 318% defatted. Defatted and undefatted seeds of papaya carica papaya were analyzed for proximate composition, some toxicants, sugar composition, mineral content.
Cytotoxicity of the carica papaya aerial parts extracts was carried out by using mtt colormetric methods. Read book chemical composition of carica papaya flower paw pawfocuses on the latex coming from its fruits of papaya cx variety. Authentic standard comparison with available reference compounds. Biochemical constituents in leaf of carica papaya ethnomedicinal plant of kachchh region article pdf available march 2014 with 5,380 reads how we measure reads. The bioactive compounds of the leaves of carica papaya. These active principles or ingredients occur naturally in such plants bamisaye, et al. Routine crude drug assays and tests tor stetoidal saponins, flavonols, tannins, phenols, organic acids, unsaturated sterols and alkaloids have been made on the leaves of carica papaya l.
Phytochemical examination of the leaves of carica papaya l. The fruit is healthy and delicious and the whole plant parts including fruit, root, bark, peel, seeds and pulp are also known to have medicinal properties. Jul 26, 2018 carica papaya is also used in the treatment of ulcers, 7 diabetics, 8 etc. The morphotypes were based on fruit shape and pulp colour and are oblong red, oblong yellow, pear orange, round orange and round yellow. K7g carica papaya ethanolic, aqueous fruit pulp, dry leaf kongkachuichai and charoensiri, 2010. The medicinal properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. The alkaloid carpaine has been isolated from the leaves of the nigerian variety of carica papaya l and some new derivatives of the alkaloid have been prepared.
Botanical description of carica papaya carica papaya is an evergreen herb, having treelike appearance, 210 m tall and usually unbranched. A students guide to tho e deadly venoms of some cowrie shells which are used seashore. Caricaceae for possible antioxidant phytochemicals, proximate nutrient constituents, amino acid composition and mineral content present in the samples using standard chemical and chromatographic procedures. Effect of carica papaya leaf extract capsule on platelet. Papaya is a large perennial herb with a rapid growth rate. This has necessitated the need for a research and development of ecofriendly. Pdf phytochemical screening, antimicrobial and antioxidant. Leaves, fruit and seeds of the carica papaya are used as ethno medicine. This work describes biochemical constituents of leaves of carica papaya. The leaves have been researched for its medicinal uses and has been documented in literature for its use by natives of various parts of the world. Moreover, the levels of these enzymes vary in the fruit. Chemical constituents of cowry cyparica samplomoneta. Drying methods had significant p of the seeds, with freezedrying.
Does carica papaya leafextract increase the platelet count. The fruit is consumed worldwide as fresh fruit and vegetable or used as processed product. Platelets are the type of blood cells produced from megakaryocytes by the action of a major hormone thrombopoietin. Chemical composition of carica papaya flower paw paw.
Carica papaya, aerial parts, anticancer activity, phytoconstituents. Carica papaya leaf decoction, an australian aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal reports. Phytochemical screening and evaluation of platelet. The results suggest that petroleum ether extract of c. Pdf chemical composition of leaves, fruit pulp and seeds in.
Fruit harvest produces various byproducts as plants are removed after finishing the production cycle approximately 2 years of continuous production, and immature or. Chemical composition of leaves, fruit pulp and seeds in. Phytochemical screening confirmed the presence of folic acid, vitamin b. Antibacterial substance from carica papaya fruit extract. Carica papaya extract papaya extract, paw paw extract. Its origin is in the tropics of the americas, perhaps. This study was carried out to screen the leaf extracts of p. Additional sources and suggested readings 1 papaya wikipedia, the free encyclopedia 2 chemical profile of unripe pulp of carica papaya pakistan journal of nutrition 4 6.
Main chemical components are papain, chymopapain, pectin. Chemical characterization and in vitro cytotoxicity on. The latex of the papaya plant and its green unripe fruits contains the proteolytic enzyme. Anticancer activity of carica papaya extracts in and. Journal of complementary and alternative medical research, issn. Jun 08, 2016 botanical description of carica papaya carica papaya is an evergreen herb, having treelike appearance, 210 m tall and usually unbranched. The alkaloid, carpaine, was isolated and identified. Cambridge university today to help victims of strokes, heart diseases and press.
In vitro antimalarial evaluations and cytotoxicity. This work describes biochemical constituents of leaves of c. Chemical constituents of cowry 542 presence of cardenolides contributes to the role f fish, j. Consequently, the resulting nonwatersoluble material is generally considered as waste, and in comparison to the water soluble fraction, little is known regarding its chemical composition 15. The leaves and fruits of five carica papaya morphotypes were harvested from trees in home gardens in umu ahia, abia state, nigeria. Phytochemical and antioxidant nutrient constituents of carica. The results in table 2 and 3 showed that carica papaya extracts were minimal toxic and showed antihiv1 activity. Pdf chemical constituents and nutrient composition of. In this study we investigated its in vitro cytotoxicity on human squamous cell carcinoma cells followed by metabolomic profiling of carica papaya leaf decoction and leaf juicebrewed leaf juice to determine the effects imparted by the. Chemical constituents and nutrient composition of carica. Chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts. Carica papaya leaves extracts for the treatment of dengue fever.
Joshi2 1department of chemistry, kskv kachchh university, bhuj 370 001, gujarat, india 2department of chemistry, saurashtra university, rajkot 360 005, rajkott, india. Both ethanol and nhexane extracts revealed the presence of alkaloids. Sarcotesta showed higher percentages of ash, crude protein, and crude fiber than did endosperm, but was lacking in fat. In traditional medicine, carica papaya leaf has been used for a wide range of therapeutic applications including skin diseases and cancer. The highland papayas, vasconcellea, are considered the nearest relatives to carica papaya although the relationship is not close aradhya et al. Evaluation of mosquito larvicidal effect of carica papaya against aedes aegypti p. In reference to the phytochemical analysis of carica papaya l. Carica papaya used in treatments of jellyfish, insect stings, skin lesions and improve damaged skin conditions. Biochemical constituents in leaf of carica papaya ethnomedicinal plant of kachchh region suhas j. As a crop, papaya is characterized by high yield and precociousness since it begins scaled production before the first year. Pdf chemical composition of papaya philippa c ojimelukwe. Chemical composition of leaves, fruit pulp and seeds in some carica papaya l morphotypes article pdf available january 2012 with,854 reads how we measure reads. Pdf chemical composition of leaves, fruit pulp and seeds. Here the attempt has been done to study the mineral constituents of leaves of c.
Pawpaw carica papaya belongs to the family caricaceae with over twenty species but only one member of the genus carica is cultivated as a fruit tree, while the other three genera cyclicomorpha, jarilla and jacaratia are grown primarily as ornamentals. The present study was designed to perform phytochemical and physicochemical analyses of carica papaya leaves, and to. Carica papaya extract engaged in supply and exports of carica papaya extract also called papaya extract or paw paw extract. Evaluation of mosquito larvicidal effect of carica coden.
Okpe oche 1, attah rosemary 1, ojowu john 1, edenta chidi 2, samuel m. Alcoholic extract 50% etoh of plant proteolytic activity, antifungal. The basic constituents of the leaves of carica papaya. Vasugi abstract the development of resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. It is a soft wooded singlestemmed perennial tree, 210 m in height, with a crown of large palmate leaves emerging from the apex of the trunk. Carica papaya contains an enzyme known as papain which is present in the bark, leaves and fruit. Sd on the phytochemicals composition and antioxidant activities of carica papaya seeds, a medicinal plant, was investigated. The seed is a rich source of proteins 278% undefatted, 444% defatted, lipids 283% undefatted and. Effect of drying methods on the phytochemicals composition. Amongst such medicinal plants is pawpaw carica papaya.
Pdf chemical composition of leaves, fruit pulp and seeds in some. The chemical constituents were analysed using gas chromatography mass spectrometry gcms. It was found that the yield of this alkaloid from the nigerian plants is markedly lower than the values reported for american and asian varieties. Pdf biochemical constituents in leaf of carica papaya. Toxic, but beneficial compounds from endophytic fungi of carica papaya. Crude latex the chemical constituents were analysed using gas chromatography mass spectrometry gcms. Chemical composition of papaya carica papaya seeds.
Anjana gv, priya d, srimathi r, shantha kumar b department of pharmaceutical chemistry, srm college of pharmacy, srm institute of science and technology, chennai, tamil nadu, india. Sensitivity, clinical isolates, urinary tract, carica papaya, extract, fractions introduction medicinal plants are cheap and renewable sources of pharmacologicallyactive substances and are known to produce certain chemicals that are naturally toxic to bacteria basile et al. Biochemical properties in peel, pulp and seeds of c. Biochemical constituents in leaf of carica papaya ethnomedicinal plant of kachchh region puhas j.
Leaves contain large amounts of alkaloids, carpaine and pseudocarpine which creates positive effects on heart as well as on respiration perry. Papaya leaves chemical profiling have been shown so many active components such as papain, chymopapain, cystatin, tocopherol, ascorbic acid, flavonoids. Pdf the leaves and fruits of five carica papaya morphotypes were harvested from trees in home gardens in umuahia, abia state, nigeria. The plants are usually shortlived, but can produce fruit for more than 20years. The decrease in the fiber could be due to the conversion of the fiber, cellulose to carbohydrate which is used during respiration.
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